Delaware Health and Social Services Division of Public Health

hMPVX (monkeypox) Vaccine Clinic


Notice: Timeslots have been filled for both this vaccine clinic and the Wilmington clinic listed below. 


Tuesday, August 23, 9 a.m. - 3 p.m.
CAMP Rehoboth Community Center
37 Baltimore Avenue, Rehoboth Beach, DE 19971

200 timeslots available
Call 302.227.5620

Second dose administered in four weeks. 
Tuesday, September 20.

When scheduling both appointments, please be mindful that your slot will be the same for both dates.


Those who should consider vaccination...

Are those engaging in high-risk activities, including sexual practices, that increase exposure to MPX such as:

  • Gay, bisexual, and other men who have sex with men and have had multiple (more than one) or any anonymous sexual partners
  • Transgender women or nonbinary persons assigned male at birth who have sex with men
  • Sex workers (of any sexual orientation/gender)
  • Staff (of any sexual orientation/gender) at establishments where sexual activity occurs (e.g., bathhouses, saunas, sex clubs)


Individuals should be aware that the vaccine, a two-dose series given 28 days apart, is not considered effective until two weeks after the second dose.


Particularly those at higher risk should continue to use preventive measures and reduce engaging in any high-risk behaviors until that time.




Wilmington Vaccine Clinic

Thursday, August 25. 


Community Service Building

100 West 10th St., Ground Floor

Wilmington, DE 19801

Clinic hours: 9 a.m. - 3 p.m.



200 timeslots available

Call 302.652.6776 between 9 a.m. - 3 p.m., Monday - Thursday. 


Second dose administered in four weeks.

Wilmington second dose date: Thursday, September 22. 


Free parking at Community Service Parking garage

11 W 11th St, Wilmington, DE 19801

(bring ticket for validation)


In coordination with AIDS Delaware & Delaware HIV Consortium.



More About hMPVX Virus

While MPX vaccine will be expanding, not everyone needs the vaccine. Unlike with COVID-19, the spread is primarily through direct contact with an infected person and not airborne transmission. Those engaging in behaviors, including intimate contact with multiple partners are at higher risk than the general public.


There are things that each person in the general public can do to protect themselves regardless of their ability to access the vaccine, such as limiting direct contact with anyone with a concerning rash, limiting the number of intimate partners, talking openly with intimate contacts about recent behaviors, and not sharing bedding, towels and eating or drinking utensils with anyone who does.


The vaccine JYENNOS, used to prevent MPX, is fully FDA approved for use against smallpox. However, if you received a previous smallpox vaccine more than three years ago, it may not provide protection now.


Most people with monkeypox do not require hospitalization and may isolate at home. Monkeypox spreads between people through direct contact with an infectious rash, body fluids, or by respiratory secretions during prolonged, face-to-face contact. The transmission of the monkeypox virus is possible from the onset of the first symptoms until the scabs have separated and the skin has fully healed.



Signs and Symptoms

The symptoms of MPX are similar to but milder than the symptoms of smallpox. Symptoms usually start within three weeks of exposure to the virus. Most people who contract MPX will develop a rash, and some will develop flu-like symptoms beforehand. The flu-like symptoms may include fever, headache, muscle aches and backache, sore throat, cough, swollen lymph nodes, chills, or exhaustion. If someone has flu-like symptoms, they usually will develop a rash one to four days later.


If you suspect you are experiencing any symptoms associated with MPX you should immediately:

  • Contact your health care provider and discuss your symptoms and concerns.
  • Self-isolate until all lesions have resolved, the scabs have fallen off, and a fresh layer of intact skin has formed.
  • Avoid being intimate with others.
  • Make a list of your close and intimate contacts in the last 21 days.


DPH launched a hotline for individuals with questions or concerns about MPX. The hotline number is 866-408-1899 and is operational Monday – Friday from 8:30 a.m. to 4:30 p.m. Questions may also be emailed to Both the hotline number and email address share staff with the COVID-19 Call Center. To learn more about MPX prevention programs and resources, visit


Town Halls

Beebe Healthcare's virtual town hall on Monkeypox virus was at 5:30 p.m. on Monday, Aug. 15. David A. Tam, MD, MBA, CPHE, FACHE, President & CEO, and Bill Chasanov, DO, Beebe’s Chief Population Health Officer, shared updates on Monkeypox as a public health concern. To watch, visit Beebe’s Facebook page for the presentation at around the eight (8) minute mark:


CAMP Rehoboth Community Center will hold a town hall on Tuesday, Aug. 16, from 7 p.m. to 8:30 p.m. addressing the MPX situation in Delaware. This town hall is in partnership with the Delaware Department of Health and Social Services. DHSS Secretary Molly Magarik will be discussing Delaware's response to the virus in the CAMP community and will field questions and concerns from community members. Joining Magarik will be Dr. Marci Drees, Chief Infection Prevention Officer and hospital epidemiologist for ChrisitanaCare. The event will be held at CAMP Rehoboth, 37 Baltimore Avenue, Rehoboth Beach. Registration is required: